Developing the next generation of cancer vaccines
Our Technology
Irazu’s vaccine program uses bacteria to do all of the work for us
Our strain of bacteria has decades of development behind it to optimally and safely create our vaccines.
How It Works
Our vaccine's origins come from bacteria which is engineered to not cause disease
Our proprietary, genetically-altered strain of bacteria is given instructions to express cancer markers of our choosing on the outside of its membrane. Think of the membrane as the bacteria’s skin.
On the cellular level, the instructions are used by the bacteria to modify its membrane to include cancer markers.
On the cellular level, the instructions are used by the bacteria to modify its membrane to include cancer markers.
With a dash of salt, the microbes begin to shed off parts of its membrane, which are called “Outer Membrane Vesicles” or OMVs for short. Think of it like a snake shedding its skin.
During this shedding, the OMVs carry with it the cancer markers we told it to make.
This is the OMV with the cancer markings on it. This is our vaccine.
How we do it
Our bacteria is given instructions to express cancer markers of our choosing
Our bacteria is given food and a warm place to grow in the lab where it can create copies of itself. This process is easy, cheap, and quick and not unlike making beer or wine!
With a dash of salt, we tell the microbes to begin making OMVs, our vaccine
Before you know it, our microbes have blebbed off tons of OMVs ready for purification
After removing debris and impurities, our OMVs are left, ready to be used to kill cancer cells
How We Cure Cancer
Our vaccine does not require any complex formulation or post-processing. The OMVs are purified, tested, and ready to administer. The vaccine doesn't even need an adjuvant.
After the vaccine is given, the patient’s own immune system will recognize the OMV, determine it is foreign, and attack it. This is a natural process that happens regularly, but in this case, the system will “learn” and remember the markings. This is a “Wanted” poster and it’s distributed to all the troops.
The patient's immune system remembers and seeks out the OMVs it mounted a response to.
When the immune system's soldier cells identify markings that were first seen on the OMVs, they engage the invader. In this case, the invader is a tumor that is expressing the cancer markings.
The result is tumor destruction and we didn't even have to do anything!